{"id":30428,"date":"2025-10-15T10:00:00","date_gmt":"2025-10-15T03:00:00","guid":{"rendered":"https:\/\/w9wellness.com\/?p=30428"},"modified":"2025-10-24T15:49:08","modified_gmt":"2025-10-24T08:49:08","slug":"familial-hypercholesterolaemia-fh","status":"publish","type":"post","link":"https:\/\/w9wellness.com\/en\/familial-hypercholesterolaemia-fh\/","title":{"rendered":"Hereditary hyperlipidemia (FH) increases the risk of heart disease at a young age."},"content":{"rendered":"

Familial Hypercholesterolaemia (FH) <\/strong>or Hereditary hyperlipidemia<\/strong> It is a condition caused by a genetic abnormality that causes the body to have bad cholesterol (LDL-C<\/strong>) tall since birth, different from normal people who usually have high fat from eating habits or lifestyle. This abnormality makes people at risk for heart disease and blood vessels faster than normal people. Some people may have heart attacks or strokes before the age of 50. Information from FH Foundation<\/a> It was found that this disease occurs approximately 1 in 250 people worldwide<\/strong> But more than 90% doesn't know he has FH.<\/strong> Therefore, we miss the opportunity for early treatment and prevention.<\/p>\n\n\n\n

Genetic mechanisms<\/strong><\/h2>\n\n\n\n

In FH patients, even with diet control or exercise, cholesterol levels remain higher than normal because The liver cannot remove LDL-C (bad cholesterol).<\/strong> Go all out<\/p>\n\n\n\n

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\"Hereditary<\/a><\/figure>\n<\/div>\n\n\n\n
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Normally, the liver uses LDLR<\/strong> (LDL receptor), APOB<\/strong> (LDLR-binding protein) and PCSK9<\/strong> (proteins that control the breakdown of LDLR) to transport cholesterol into the liver for disposal. But when these genes are abnormal, LDL-C remains in the blood in excessive amounts and accumulates on the artery walls, resulting in Atherosclerosis, acute heart attack, and stroke<\/strong><\/p>\n<\/div>\n<\/div>\n\n\n\n

Report from <\/em>US CDC<\/em><\/strong> It points out that if left untreated, FH patients are at higher risk of heart disease than the general population. <\/em>22 times<\/em><\/strong><\/p>\n\n\n\n

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Make an appointment to consult with us<\/a><\/div>\n<\/div>\n\n\n\n

Genetic transmission<\/strong><\/h2>\n\n\n\n

This disease is transmitted in a Autosomal dominant<\/strong> This means that if one father or mother has FH, each child has a chance. 50% <\/strong>To get the abnormal gene and become a patient as well.<\/p>\n\n\n\n

example<\/strong><\/p>\n\n\n\n