• Deficiency of many vitamins. including vitamin D deficiency Correlated with depression. • Low levels of vitamin D. It can affect mood regulation, decision-making, and behavior.• Vitamin D is not a cure for depression. But vitamin D compensation in people with low levels May help in regulating emotions and can increase the quality of sleep. Depression is a chronic disease. which is considered another social problem which is becoming more intense every year Both in terms of quality of life of the patient Social burden on those around you and skyrocketing suicide rates Treating depression using medication along with psychotherapy. There is a 76-85% success rate (WHO 2020), but the problem is that fewer than 25% patients receive treatment. And there is another part that doesn't want to take medicine. Because of fear of addiction to drugs Or maybe because they can't stand the side effects [1] because depression is a chronic disease. which can come back again Especially those who do not receive treatment continuously. It was found that there was a higher rate of recurrence. Therefore, efforts began to be made to look for factors. or other combination methods of treatment Especially in the area of nutritional status, nutrients or vitamin supplements [2], we are starting to have more and more research. that found a relationship between the deficiency of many vitamins, nutrients, or minerals and depression, such as vitamin B3, vitamin B [...]