Even if we get enough sleep, eat well and exercise regularly, many people still feel “not as energetic” or “unexplained brain fatigue.” One important factor that is often overlooked is the level of NAD+ (Nicotinamide Adenine Dinucleotide) It is an important biomolecule in every cell of the body and tends to decrease with age.
NAD+ It is a coenzyme found in every human cell and plays an important role in converting energy from food into usable energy for cells in the form of: ATP (Adenosine Triphosphate) It is also a precursor to DNA components. When NAD+ levels are low, energy production and cellular repair processes are impaired, which can be associated with fatigue, cognitive decline, and signs of cellular aging.
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Think of NAD+ as an “energy bridge” connecting the food we eat to the energy our cells actually use (ATP). When this bridge weakens, cells produce less energy, the brain may become fatigued, and repair systems slow down. But when NAD+ levels are balanced, cellular mechanisms return to functioning efficiently, including gene function. Sirtuins (SIRT1–SIRT7) Which is related to the flexibility of cell age, it will also work more balanced.
note: Some evidence comes from mechanistic and animal studies, such as: Harvard Medical School “Rewinding the clock” which still needs further human studies to confirm its effectiveness directly
level NAD+ It can be changed by many factors. A review of human studies found the following associations:
Boost energy and metabolism
NAD+ works with enzymes in mitochondria to create ATP energy. When NAD+ levels are optimal, the body can produce energy more efficiently and may help you feel more energetic throughout your day, especially in those with high energy needs.
Supports the brain and nervous system
NAD+ is a major energy source for neurons and is involved in memory and brain function. Harvard Medical School (2020) Increasing NAD+ in the blood vessels of aged animal models has been reported to restore brain circulation and support neuronal health.
Balance metabolism and control weight
NAD+ is involved in fat metabolism (β-oxidation) and blood glucose homeostasis. Work from Nature Portfolio (2023) It has been shown that NAD+ supplementation may contribute to improving mitochondrial performance in people over 40.
| Issue | NR/NMN (Dietary Supplement) | NAD+ IV Therapy |
| type | Eat at home | Intravenous fluids in the clinic |
| mechanism | Precursor converted to NAD+ | It is NAD+ directly into the bloodstream. |
| The speed at which feelings change | Take it slowly and eat it regularly. | It is generally faster because it is given directly. |
| Scaling/Formula | Fixed according to product label | The dosage can be adjusted by a doctor according to your physical condition. |
| Tracking | Users mainly follow themselves. | There is an assessment and follow-up by a doctor/nursing team. |
*Results vary from person to person. Human evidence is still evolving.
• Reference overview mechanism: Nature Reviews Mol Cell Biol : https://www.nature.com/articles/s41580-020-00313-x | PubMed (Xie 2020) : https://pubmed.ncbi.nlm.nih.gov/33028824/
Overall safety
Intravenous NAD+ administration should be performed in a standardized medical facility under the supervision of a physician and professional nurse, with pre-treatment health screening and monitoring during administration.
Results vary from person to person, depending on physical condition and doctor's assessment.
All treatments NAD+ at W9 Wellness Center is administered by professionally trained nurses. Under Supervision and care by a physician specializing in anti-aging medicine. Before receiving treatment, the service recipient will receive: Evaluate and consult with a doctor To provide guidelines that are appropriate for each individual's health and goals.
Let W9 Wellness be a part of your compassionate care by restoring balance from the inside out to the cellular level, leaving you feeling energized, refreshed, and ready to live life with confidence once again.
Q: Is NAD+ IV safe?
A: Safe when under the care of professional doctors and nurses.
Q: How should I prepare before doing NAD+ IV?
A: Get enough rest, drink plenty of water, and inform your health history before receiving the service.
Q: How often should I do this?
A: It is generally recommended 1–2 times per month, or consult your doctor based on your health goals.
Q: Can this be used in conjunction with Vitamin IV Drip?
A: They are often used together to support energy and restore overall health.
Q: Why do NAD+ levels decrease with age?
A: Reviews suggest that it is related to increased NAD+ degrading enzymes (such as CD38), PARP activation from DNA damage, and certain lifestyle factors such as irregular sleep, nutrition, and alcohol. The effects vary from person to person.
Getting enough sleep but still feeling tired? Eating the same amount but gaining weight? Mood swings, irritability, or feeling unmotivated to live life?
